Precision Indirect Calorimeters for Accurate Metabolic Assessment

Explore advanced indirect calorimetry systems tailored for healthcare, fitness, and research, with B2B-ready integrations across North America.

Advancing Cellular Metabolic Research


Understanding cellular metabolism is critical to breakthroughs in fields like cancer research, immunology, and drug development. Seahorse XF Analyzers have emerged as a gold standard in metabolic analysis, enabling real-time measurement of mitochondrial respiration and glycolysis in live cells. These systems offer a non-invasive, label-free platform that tracks metabolic activity with extraordinary accuracy, enabling researchers to interpret how cells use energy under various conditions.

Environmental Metabolic delivers high-performance Seahorse XF Analyzers to B2B clients across North America. As a trusted provider of integrated technologies, we help streamline bioenergetic research with best-in-class instrumentation, intuitive software, and scalable service packages. With advanced tools and tailored support, we empower organizations to enhance productivity, reduce complexity, and generate reproducible data. Our commitment to continuous product development and expert guidance helps your team confidently achieve meaningful results.

Based in Oakland, CA, Environmental Metabolic leads with innovation, reliability, and a client-focused approach.

Top-Tier Technologies from Environmental Metabolic and Global Partners


In addition to offering products and systems developed by our team and trusted partners for Gas Analyzers, we are proud to carry top-tier technologies from Global Advanced Operations Tek Inc. (GAO Tek Inc.) and Global Advanced Operations RFID Inc. (GAO RFID Inc.). These reliable, high-quality products and systems enhance our ability to deliver comprehensive technologies, integrations, and services you can trust. Where relevant, we have provided direct links to select products and systems from GAO Tek Inc. and GAO RFID Inc.

Core Components

Software

 

  • Wave Software Suite: Designed specifically for XF Analyzers, it supports assay design, kinetic data acquisition, normalization, and multi-sample comparison.
  • Data Visualization Tools: Graphing and analysis modules allow teams to explore trends across biological replicates and experimental groups.

Cloud Services

 

  • Remote Monitoring & Storage: Secure cloud backup of real-time data with configurable access levels.
  • Collaboration Portals: Share experiments and insights across distributed B2B teams in North America.
  • Updates & QA Logs: Auto-pushed firmware and calibration logs for compliance and reproducibility.

Hardware

  • Seahorse XF Extracellular Flux Analyzer – Utilizes Chemical and Gas Sensors to precisely measure OCR and ECAR for real-time metabolic profiling.
  • Sensor Cartridges & Utility Plates – Supported by IoT Accessories to enable accurate, single-use multiplex assay performance.
  • Temperature-Controlled Incubation Chambers – Integrated with Temperature & Process Calibrators to maintain assay consistency in non-CO₂ environments.
  • High-throughput Automation Modules – Powered by Device Edge solutions for scalable XF96 and XF384 format operation in B2B lab environments.
  • GAO Tek-integrated Lab Instruments – Enhanced with Healthcare IoT components to expand analytical capacity with specialized readers and fluidic controls.

01.

Key Features and Functionalities

 

  • Real-time bioenergetic profiling of live cells
  • Simultaneous measurement of mitochondrial and glycolytic function
  • Low cell number requirement (as few as 10,000 cells/well)
  • XF Cell Mito Stress Test and Glycolysis Stress Test protocols
  • No labeling, washing, or endpoint reagents required
  • Normalization tools for cell count and protein content
  • Intuitive drag-and-drop assay design
  • Exportable datasets for custom statistical analysis

02.

Benefits

  • Non-destructive, label-free measurements
  • Highly reproducible, real-time metabolic data
  • Accelerates drug discovery and translational research timelines
  • Reduces manual error through automation-ready interfaces
  • Designed for B2B research scalability in academic, biotech, and pharma sectors
  • Backed by Environmental Metabolic’s North American service network and expert technical support

03.

Compatibility

 

  • Supports adherent and suspension cell types
  • XF24, XF96, and XF384 formats available for scalable throughput
  • Compatible with mammalian, yeast, insect, and microbial cells
  • Integrates with standard biological workflows in oncology, immunology, and metabolic disease research

04.

Integrations

 

  • Compatible with automated liquid handlers for streamlined workflows
  • LIMS-ready via open API for seamless data migration
  • Interfaces with GAO RFID lab tracking systems for asset traceability and audit trails
  • Integrates with real-time imaging systems and optical readers for synchronized metabolic and morphological data

05.

Industries Served

  • Biotechnology and Pharmaceuticals
  • Academic Research Institutions
  • Contract Research Organizations (CROs)
  • Clinical Research Labs
  • Nutraceutical Development
  • Environmental Toxicology

06.

Applications

  • Cancer metabolism and mitochondrial dysfunction studies
  • Drug efficacy and cytotoxicity profiling
  • Immunometabolism investigations in T cells and macrophages
  • Metabolic phenotyping of engineered cell lines
  • Stem cell bioenergetics and differentiation
  • Microbial and yeast respiration assays

Relevant U.S. & Canadian Industry Standards

Health Canada Guidelines for Medical Device Testing

FDA 21 CFR Part 11

ISO 13485

GLP (Good Laboratory Practice) Compliance

CLIA (Clinical Laboratory Improvement Amendments)

Case Studies

Oncology Lab in New York City

A biotech firm in NYC used Seahorse XF Analyzers from Environmental Metabolic to assess mitochondrial respiration in glioblastoma cells, optimizing their drug pipeline by reducing assay time by 40%.

Immunology Department, Texas University

An academic lab in Texas partnered with Environmental Metabolic to deploy Seahorse XF96 Analyzers for T-cell metabolic profiling, leading to new insights into immune exhaustion mechanisms.

Biomedical Center in Toronto

A Canadian research institute adopted Seahorse XF solutions from Environmental Metabolic, integrating them with GAO RFID-based asset tracking to enhance compliance and improve equipment utilization across shared core labs.

Ready to elevate your metabolic research capabilities with Seahorse XF Analyzers?

Contact Environmental Metabolic today for detailed product information, pricing, expert consultation, or technical support. Our team is here to help you make confident, future-ready decisions.

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